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Prof. Marcin Drąg, DSc, PhD
Email: marcin.drag@pwr.edu.pl
Unit: Faculty of Chemistry » Department of Chemical Biology and Bioimaging
Wybrzeże Wyspiańskiego 29, 50-371 Wrocław
building A-2, room 116
phone +48 71 320 4526
Research fields
- Chemical biology; combinatorial chemistry; proteolytic enzymes; peptide synthesis; activity-based probes.
Recent papers
2018
- Poręba M., Rut W., Vizovisek M., Groborz K., Kasperkiewicz P., Finlay D., Vuori K., Turk D., Turk B., Salvesen G.S., Drąg M., Selective imaging of cathepsin L in breast cancer by fluorescent activity-based probes Chemical Science 2018, 1.
2017
- Poręba M., Salvesen G.S., Drąg M., Synthesis of a HyCoSuL peptide substrate library to dissect protease substrate specificity Nature Protocols 2017, 12, 2189.
- Kasperkiewicz P., Altman Y., D'Angelo M., Salvesen G.S., Drąg M., A toolbox of fluorescent probes for parallel imaging reveals uneven location of serine proteases in neutrophils Journal of the American Chemical Society 2017, 139, 10115.
2014
- Kasperkiewicz P., Poręba M., Snipas S. J., Parker H., Winterbourn C.C., Salvesen G.S., Drąg M., Design of ultrasensitive probes for human neutrophil elastase through hybrid combinatorial substrate library profiling. Proc. Natl. Acad. Sci. U.S.A. 2014, 111, 2518.
2010
- Drąg M., Salvesen G.S., Emerging principles in protease-based drug discovery. Nature Reviews Drug Discovery 2010, 9, 690.